Trial Projects

The purpose of the study was to evaluate the efficacy of ASP0113 compared with placebo as measured by a primary composite endpoint of overall mortality and CMV end organ disease (EOD) through 1 year post-transplant. Safety of ASP0113 in participants undergoing allogeneic HCT will also be evaluated.

The main objectives of this trial are: 1.) Demonstration of non-inferiority of VCD induction therapy compared to PAd induction therapy with respect to response rate (very good partial remission or better; response criteria of the International Myeloma Working Group, IMWG).

2.) Determination of the best of four treatment strategies with respect to progression-free survival (PFS). The four treatment strategies are defined by PAd vs. VCD induction treatment, standard intensification therapy, ...

Study Design The study included a lenalidomide cohort and a background cohort. Patients in both cohorts had received ≥ 1 prior antimyeloma therapy and were required to have never received lenalidomide. Enrolled patients who were treated on the study with lenalidomide for off-label indications were kept in the study. To achieve a patient population reflective of those treated in real-world clinical practice, there were few restrictions on eligibility. Exclusion criteria were refusal to participate ...

An example project, showing how the metadata scheme should be filled.

The present study is a feasibility study. The aim is to develop intensified and needs-oriented support for the return to work of oncological patients with uncertain vocational reintegration prognosis by counselors in cancer counseling centers and to investigate the acceptance, feasibility and implementation conditions. Within the feasibility study, survey data of advice seekers with and without intensified counseling will be collected. The recruitment of the advice seekers is a sequential survey ...